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Antibody-Drug Conjugates (ADCs)
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Antibody-Drug Conjugates (ADCs)

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Catalog Product Name CAS Number
BADC-01610 Tisotumab vedotin 1418731-10-8
Tisotumab vedotin is an antibody-drug conjugate comprising a fully human monoclonal antibody specific for tissue factor (TF-011) conjugated to monomethyl auristatin E (MMAE). Tisotumab vedotin has been approved for the treatment of adult patients with recurrent or metastatic cervical cancer with disease progression on or after chemotherapy. Inquiry
BADC-01611 Farletuzumab ecteribulin 2407465-18-1
Farletuzumab ecteribulin is an antibody-drug conjugate consisting of the humanized antifolate receptor-alpha (FRα) monoclonal antibody conjugated to eribulin by a cathepsin B-cleavable linker. Inquiry
BADC-01612 Moxetumomab pasudotox 1020748-57-5
Moxetumomab pasudotox is a recombinant immunotoxin composed of the Fv fragment of an anti-CD22 monoclonal antibody fused to a 38-kDa fragment of Pseudomonas exotoxin A, called PE38. Moxetumomab pasudotox has been used in the study of acute lymphoblastic leukemia (ALL). Inquiry
BADC-01613 Zilovertamab vedotin
Zilovertamab vedotin is a receptor tyrosine kinase-like orphan receptor 1 (ROR1) targeting antibody-drug conjugate consisting of zilovertamab, a proteolytically cleavable linker, and the antimicrotubule agent monomethyl auristatin E. Inquiry
BADC-01614 Glembatumumab vedotin 1182215-65-1
Glembatumumab vedotin is an antibody-drug conjugate consisting of a fully human IgG2 monoclonal antibody (CR011) against gpNMB conjugated to the microtubule inhibitor, monomethyl auristatin E (MMAE). Glembatumumab vedotin exhibits anticancer activity. Inquiry
BADC-01615 Trastuzumab duocarmazine 1642152-40-6
Trastuzumab duocarmazine is a HER2-targeting antibody-drug conjugate comprised of trastuzumab bound to a linker drug containing duocarmycin. Trastuzumab duocarmazine has been used in the research of HER2-positive locally advanced or metastatic breast cancer therary. Inquiry
BADC-01616 Cantuzumab ravtansine 868747-45-9
Cantuzumab ravtansine is an antibody-drug conjugate comprised of a humanized monoclonal antibody cantuzumab (huC242) linked to a cytotoxic agent, ravtansine (DM4). Inquiry
BADC-02000 Indatuximab ravtansine 1238517-16-2
Indatuximab ravtansine is an antibody-drug conjugate that binds to CD138, which is overexpressed on multiple myeloma (MM) cells. Inquiry
BADC-02001 Oportuzumab monatox 945228-48-8
Oportuzumab monatox is a recombinant fusion protein consists of a monoclonal antibody targeting epithelial cell adhesion molecule (EpCAM) conjugated with a truncated form of Pseudomonas exotoxin A. Oportuzumab monatox is developed for the treatment of high-risk non-muscle invasive bladder cancer (NMIBC). Inquiry
BADC-02002 Lorvotuzumab mertansine 1008106-64-6
Lorvotuzumab mertansine is an ADC consists of a CD56-targeting antibody conjugated with an antimitotic agent. Lorvotuzumab mertansine is designed for the treatment of CD56-expressing cancers. Inquiry
BADC-02020 DEDN6526A
DEDN6526A is an antibody-drug conjugate (ADC) composed of a humanized IgG1 monoclonal antibody against anti-endothelin B receptor (ETBR) and the tubulin inhibitor monomethyl auristatin E (MMAE). DEDN6526A was developed for the treatment of Metastatic or Unresectable Melanoma. Inquiry
BADC-02029 ADCT-901
ADCT-901 is an antibody-drug conjugate (ADC) composed of a humanized monoclonal antibody (3A4) directed against human KAAG1 and conjugated through a cathepsin-cleavable linker to SG3199, a PBD-dimer cytotoxin. KAAG1 is highly and selectively expressed on tumor cell surface. Inquiry
BADC-02030 Mirvetuximab-MMAE
Mirvetuximab-MMAE is an antibody-drug conjugate (ADC) composed of a monoclonal antibody against FOLR1 and the tubulin inhibitor monomethyl auristatin E (MMAE). Mirvetuximab-MMAE can be used in the research of FRα-positive cancers. Inquiry
BADC-02031 Codrituzumab-MMAE
Codrituzumab-MMAE is an antibody-drug conjugate (ADC) composed of a monoclonal antibody against GPC3 (glypican-3) and the tubulin inhibitor monomethyl auristatin E (MMAE). Codrituzumab could induce antibody-dependent cellular cytotoxicity (ADCC) and inhibit tumor growth. Inquiry
BADC-02032 Ags-16C3F
Ags-16C3F is an antibody-drug conjugate (ADC) composed of a monoclonal antibody against ENPP3/CD203c and the microtubule inhibitor monomethyl auristatin F (MMAF). Ags-16C3F is under investigation for the treatment of metastatic renal cell carcinoma. Inquiry
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