Thailanstatin A - CAS 1426953-21-0

Thailanstatin A - CAS 1426953-21-0 Catalog number: BADC-00707

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Thailanstatin A is a splicesosome inhibitor that acts via suppressing RNA-polymerase II. It is effective against cancers, and can be used as a payload for ADCs.

General Information

Category
ADCs Cytotoxin
Product Name
Thailanstatin A
CAS
1426953-21-0
Catalog Number
BADC-00707
Molecular Formula
C28H41NO9
Molecular Weight
535.63

Chemical Structure

  • Thailanstatin A

Ordering Information

Catalog Number Size Price Stock Quantity
BADC-00707 5 mg $299 In stock
BADC-00707 10 mg $588 In stock
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Purity
95%
Appearance
Solid
Synonyms
1,6-Dioxaspiro[2.5]octane-5-acetic acid, 7-[(1E,3E)-5-[(2S,3S,5R,6R)-5-[[(2Z,4S)-4-(acetyloxy)-1-oxo-2-penten-1-yl]amino]tetrahydro-3,6-dimethyl-2H-pyran-2-yl]-3-methyl-1,3-pentadien-1-yl]-8-hydroxy-, (3R,5S,7R,8R)-
Solubility
Soluble in DMSO
Storage
Store at -20°C
Boiling Point
757.3±60.0°C at 760 mmHg
Density
1.2±0.1 g/cm3
Canonical SMILES
CC1CC(C(OC1CC=C(C)C=CC2C(C3(CC(O2)CC(=O)O)CO3)O)C)NC(=O)C=CC(C)OC(=O)C
InChI Key
GJKQDOMCDFJANR-FUDLAKRJSA-N
InChI
InChI=1S/C28H41NO9/c1-16(7-10-24-27(34)28(15-35-28)14-21(38-24)13-26(32)33)6-9-23-17(2)12-22(19(4)37-23)29-25(31)11-8-18(3)36-20(5)30/h6-8,10-11,17-19,21-24,27,34H,9,12-15H2,1-5H3,(H,29,31)(H,32,33)/b10-7+,11-8-,16-6+/t17-,18-,19+,21+,22+,23-,24+,27+,28+/m0/s1

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