Description
(R)-8-Azido-2-(Fmoc-amino)octanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
(2R)-8-azido-2-(9H-fluoren-9-ylmethoxycarbonylamino)octanoic acid
IUPAC Name
(2R)-8-azido-2-(9H-fluoren-9-ylmethoxycarbonylamino)octanoic acid
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CCCCCCN=[N+]=[N-])C(=O)O
InChI
InChI=1S/C23H26N4O4/c24-27-25-14-8-2-1-3-13-21(22(28)29)26-23(30)31-15-20-18-11-6-4-9-16(18)17-10-5-7-12-19(17)20/h4-7,9-12,20-21H,1-3,8,13-15H2,(H,26,30)(H,28,29)/t21-/m1/s1
InChIKey
ORGUFSNMGCTGEA-OAQYLSRUSA-N
Shipping
-20°C (International: -20°C)