Description
Azido-PEG3-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
Azide-PEG3-Carboxylic acid;N3-PEG3-COOH; Azido-PEG3-C2-acid; N3-PEG3-CH2CH2COOH; Azido-PEG3-propionic acid; 12-Azido-4,7,10-trioxadodecanoic acid; Propanoic acid, 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-
IUPAC Name
3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]propanoic acid
Canonical SMILES
C(COCCOCCOCCN=[N+]=[N-])C(=O)O
InChI
InChI=1S/C9H17N3O5/c10-12-11-2-4-16-6-8-17-7-5-15-3-1-9(13)14/h1-8H2,(H,13,14)
InChIKey
VWJGWKZZFZMGGY-UHFFFAOYSA-N
Solubility
Soluble in DMSO (10 mm)
Application
Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture.
Appearance
Colorless Liquid
Shipping
Room temperature
Storage
Store at 2-8°C, keep in dry and avoid sunlight