Description
m-PEG6-NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
2,5-dioxopyrrolidin-1-yl 2,5,8,11,14,17-hexaoxaicosan-20-oate
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Canonical SMILES
COCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
InChI
InChI=1S/C18H31NO10/c1-23-6-7-25-10-11-27-14-15-28-13-12-26-9-8-24-5-4-18(22)29-19-16(20)2-3-17(19)21/h2-15H2,1H3
InChIKey
KIIPLYSZOISNAS-UHFFFAOYSA-N
Flash Point
257.8±32.9 °C
Index Of Refraction
1.489
Vapor Pressure
0.0±1.3 mmHg at 25°C
Appearance
Colorless Liquid
Shelf Life
0-4℃ for short term (days to weeks), or -20℃ for long term (months).
Shipping
Room temperature
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Boiling Point
502.6±60.0 °C at 760 mmHg