Description
m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
m-PEG3-amine; 2-[2-(2-Methoxyethoxy)ethoxy]ethylamine; mPEG3-NH2; 2-(2-(2-methoxyethoxy)ethoxy)ethan-1-amine; Ethanamine, 2-[2-(2-methoxyethoxy)ethoxy]-; Methyl-PEG3-amine; 3,6,9-Trioxadecane-1-amine; 3,6,9-Trioxa-1-aminodecane
IUPAC Name
2-[2-(2-methoxyethoxy)ethoxy]ethanamine
Canonical SMILES
COCCOCCOCCN
InChI
InChI=1S/C7H17NO3/c1-9-4-5-11-7-6-10-3-2-8/h2-8H2,1H3
InChIKey
OKUWOEKJQRUMBW-UHFFFAOYSA-N
Density
0.978±0.06 g/cm3 (Predicted)
Solubility
Soluble in DCM, DMF, DMSO, Water
Index Of Refraction
1.431
Biological Activity
m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Appearance
Pale Yellow or Colorless Oily Matter
Shelf Life
0-4℃ for short term (days to weeks), or -20℃ for long term (months).
Shipping
Room temperature, or blue ice upon request.
Boiling Point
223.9±20.0°C at 760 mmHg