Description
m-PEG11-Amino is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
m-PEG11-amine; mPEG11-NH2; 2,5,8,11,14,17,20,23,26,29,32-Undecaoxatetratriacontan-34-amine; 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine
IUPAC Name
2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Canonical SMILES
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
InChI
InChI=1S/C23H49NO11/c1-25-4-5-27-8-9-29-12-13-31-16-17-33-20-21-35-23-22-34-19-18-32-15-14-30-11-10-28-7-6-26-3-2-24/h2-24H2,1H3
InChIKey
SWAJVHMMXALQKJ-UHFFFAOYSA-N
Density
1.070±0.06 g/cm3 (Predicted)
Solubility
Soluble in DMSO (10 mm)
Biological Activity
m-PEG11-Amino is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Appearance
Pale Yellow or Colorless Oily Liquid
Shelf Life
-20℃ 3 years powder; -80℃ 2 years in solvent
Shipping
Room temperature, or blue ice upon request.
Boiling Point
551.9±45.0 °C at 760 mmHg