Leptomycin B - CAS 87081-35-4

Leptomycin B - CAS 87081-35-4 Catalog number: BADC-00789

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a potent anti-fungal antibiotic. Leptomycin B is an inhibitor of export protein CRM1.

General Information

Category
ADCs Cytotoxin
Product Name
Leptomycin B
CAS
87081-35-4
Catalog Number
BADC-00789
Molecular Formula
C33H48O6
Molecular Weight
540.73

Chemical Structure

  • Leptomycin B

Ordering Information

Catalog Number Size Price Stock Quantity
BADC-00789 1 mg $299 In stock
BADC-00789 1 g $499 In stock
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Appearance
White to Pale Yellow Solid
Synonyms
19-(3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-Nonadecapentaenoic Acid; Elactocin; Mantuamycin; Antibiotic CI 940; PD 114720
Solubility
Soluble in DMSO, Methanol
Storage
-20 °C
Boiling Point
725.8°C at 760 mmHg
Melting Point
>56°C(dec.)
Density
1.072 g/cm3
Canonical SMILES
CCC(=CC(C)CC=CC(=CC(C)C(=O)C(C)C(C(C)CC(=CC(=O)O)C)O)C)C=CC1C(C=CC(=O)O1)C
InChI Key
YACHGFWEQXFSBS-XYERBDPFSA-N
InChI
InChI=1S/C33H48O6/c1-9-28(14-15-29-24(5)13-16-31(36)39-29)19-22(3)12-10-11-21(2)17-25(6)32(37)27(8)33(38)26(7)18-23(4)20-30(34)35/h10-11,13-17,19-20,22,24-27,29,33,38H,9,12,18H2,1-8H3,(H,34,35)/b11-10+,15-14+,21-17+,23-20+,28-19-/t22-,24+,25-,26+,27-,29+,33-/m1/s1
Source
Streptomyces sp.

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