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Leptomycin A - CAS 87081-36-5 Catalog number: BADC-00788
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a potent anti-fungal antibiotic. Leptomycin A is a highly specific inhibitor of export protein CRM1.
General Information
Category
ADCs Cytotoxin
Product Name
Leptomycin A
CAS
87081-36-5
Catalog Number
BADC-00788
Molecular Formula
C32H46O6
Molecular Weight
526.71
Chemical Structure
Purity
>99% by HPLC
Appearance
Colourless Film
Synonyms
Jildamycin; Antibiotic ATS 1287A; Antibiotic PD 118607; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo-
Solubility
Soluble in ethanol or methanol. Poor water solubility. Ethanol recommended. Unstable in DMSO
Storage
-20 °C
Boiling Point
717.7°C at 760 mmHg
Density
1.079 g/cm3
Canonical SMILES
CC1C=CC(=O)OC1C=CC(=CC(C)CC=CC(=CC(C)C(=O)C(C)C(C(C)CC(=CC(=O)O)C)O)C)C
InChI Key
QECBVZBMGUAZDL-DLWOFZAMSA-N
InChI
InChI=1S/C32H46O6/c1-20(16-22(3)12-14-28-24(5)13-15-30(35)38-28)10-9-11-21(2)17-25(6)31(36)27(8)32(37)26(7)18-23(4)19-29(33)34/h9,11-17,19-20,24-28,32,37H,10,18H2,1-8H3,(H,33,34)/b11-9+,14-12+,21-17+,22-16+,23-19+
Source
Streptomyces sp.
