Eudesmine - CAS 526-06-7

Eudesmine - CAS 526-06-7 Catalog number: BADC-00218

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Lignan , from plants of the Rutaceae family, a substance presenting an estrogenic activity and sedative effects. .

General Information

Category
ADCs Cytotoxin
Product Name
Eudesmine
CAS
526-06-7
Catalog Number
BADC-00218
Molecular Formula
C22H26O6
Molecular Weight
386.44

Chemical Structure

  • Eudesmine
Purity
97 % (TLC).
Appearance
Solid powder
Synonyms
(1R,3aα,6aα)-1,4α-Bis(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan;
Solubility
chloroform; very slightly in alcohol and acetone; not in water.
Storage
Store at +4 °C, in dark place.
Application
ADCs Cytotoxin
Quality Standard
Enterprise Standard
Shipping
Room temperature
Melting Point
107-108 °C.
Density
1.2±0.1 g/cm3
Quantity
Milligrams-Grams
1.[Eudesmane sesquiterpenes from twigs of Manglietia hookeri].
Qi MG, Zhang F, Wang WS, Wu HB, Yuan HC, Jiao YG, Dong XJ. Zhongguo Zhong Yao Za Zhi. 2015 Aug;40(16):3229-32.
Chemical constituents from the acetone extract of twigs of Manglietia hookeri were isolated and purified by various column chromatographic methods over silica gel and sephadex LH-20, and preparative TLC. The structures of these compounds were identified on the basis of physicochemical properties and spectral analysis, including NMR and MS spectra. Six eudesmane sesquiterpenes were obtained and their structures were identified as trans-eudesmane-4, 11-diol(1), β-eudesmol(2), (-) -10-epi-5β-hydroxy-β-eudesmol (3), epi-carrisone (4), 6-hydroxy-eudesm-4(14) -ene(5) and gynurenol(6). All the compounds were isolated from this plant for the first time. Furthermore, the 13C-NMR data of compound 3 were reported for the first time.
2.New eudesmane-type sesquiterpenoids from the root bark of Pseudolarix kaempferi.
Jiang HL1,2, Ha W1, Shi YP1. J Asian Nat Prod Res. 2015 Dec;17(12):1180-7. doi: 10.1080/10286020.2015.1117455. Epub 2015 Dec 14.
The phytochemical investigation of the root bark of Pseudolarix kaempferi yielded eight eudesmane-type sesquiterpenoids, including three new ones, 1α-hydroxyl-4(14)-en-β-dihydroagarafuran (1), 1α, 2α-diacetoxy-8β-isobutanoyloxy-9α-benzoyl oxy-15-β-(β-furancarbonyloxy)-4β, 6β-dihydroxy-β-dihydroagarofuran (7), and 1α-acetoxy-2 α-furancarbonyloxy-8β-isobutanoyloxy-9α-benzoyloxy-15β-(β-acetoxy)-4β, 6β-dihydroxy-β-dihydroagarofuran (8). Herein the new compounds 7 and 8 were reported as a mixture. The molecular structures of the isolated compounds were elucidated on the basis of extensive spectroscopic analysis, including UV, IR, NMR, and MS, and comparison with the literature data.

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Historical Records: Ald-Ph-amido-PEG1-C2-NHS ester | FR-901464 | Trachelanthamine | Mal-PEG6-NHS | DBCO-NHCO-PEG4-amine | m-PEG3-NHS ester | m-PEG7-CH2COOH | Amino-bis-PEG3-TCO | Mal-PEG2-VCP-NB | MMAF | Eudesmine
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