Dolastatin 15 - CAS 123884-00-4

Dolastatin 15 - CAS 123884-00-4 Catalog number: BADC-00812

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Dolastatin 15 (DLS 15), a depsipeptide derived from Dolabella auricularia, is a potent antimitotic agent structurally related to the antitubulin agent Dolastatin 10. Dolastatin 15 induces cell cycle arrest and apoptosis in multiple myeloma cells. Dolastatin 15 can be used as an ADC cytotoxin.

General Information

Category
ADCs Cytotoxin
Product Name
Dolastatin 15
CAS
123884-00-4
Catalog Number
BADC-00812
Molecular Formula
C45H68N6O9
Molecular Weight
837.06 g/mol

Chemical Structure

  • Dolastatin 15
Purity
≥98%
Appearance
Lyophilized solid
Synonyms
DOLASTATIN 15; (5S)-1-[(2S)-O-(N,N-DIMETHYL-VAL-VAL-N-ME-VAL-PRO-PRO)-2-HYDROXYISOVALERYL]-2-OXO-4-METHOXY-5-BENZYL-3-PYRROLINE; (5S)-1-[(2S)-O-(N,N-VAL-VAL-N-ME-VAL-PRO-PRO)-2-HYDROXYISOVALERYL]-2-OXO-4-METHOXY-5-BENZYL-3-PYRROLINE; (5S)-1-[(2S)-O-(N,N-Dim
Solubility
10 mM in DMSO
Storage
-20°C
Shelf Life
≥ 2 years
Shipping
Room temperature
Canonical SMILES
CC(C)C(C(=O)N(C)C(C(C)C)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)OC(C(C)C)C(=O)N3C(C(=CC3=O)OC)CC4=CC=CC=C4)NC(=O)C(C(C)C)N(C)C
InChI Key
LQKSHSFQQRCAFW-CCVNJFHASA-N
InChI
InChI=1S/C45H68N6O9/c1-26(2)36(46-40(53)37(27(3)4)47(9)10)42(55)48(11)38(28(5)6)43(56)49-22-16-20-31(49)41(54)50-23-17-21-32(50)45(58)60-39(29(7)8)44(57)51-33(34(59-12)25-35(51)52)24-30-18-14-13-15-19-30/h13-15,18-19,25-29,31-33,36-39H,16-17,20-24H2,1-12H3,(H,46,53)/t31-,32-,33-,36-,37-,38-,39-/m0/s1
Sequence
N(Me2)Val-Val-N(Me)Val-Pro-Pro-OVal-Unk

View All ADCs Cytotoxin Sort Specific Products

View All ADCs Cytotoxin with Linkers Sort Specific Products

View All ADCs Linker Sort Specific Products

Related Products

Get in Touch

Verification code
Historical Records: Mal-PEG3-C1-NHS ester | MC-Gly-Gly-Phe | N-Succinimidyl 3-(Bromoacetamido)propionate | Ac-S-PEG8-NHS | APN-PEG4-tetrazine | (S)-2-(N-Methyl-3-(Methyldisulfanyl)propanamido)propanoic Acid | Propargyl-PEG9-bromide | NH2-PEG4-CH2CH2COOH | Mal-PEG-NHS | Bis-PEG9-acid | Dolastatin 15
Inquiry Basket