Description
BocNH-PEG4-acid is a cleavable ADC linker used as a linker for antibody-drug conjugates and a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Synonyms
2,2-Dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azanonadecan-19-oic acid; t-Boc-N-amido-PEG4-CH2CO2H; BocNH-PEG4-CH2COOH; 14-(Boc-amino)-3,6,9,12-tetraoxatetradecan-1-oic Acid
IUPAC Name
2-[2-[2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
Canonical SMILES
CC(C)(C)OC(=O)NCCOCCOCCOCCOCC(=O)O
InChI
InChI=1S/C15H29NO8/c1-15(2,3)24-14(19)16-4-5-20-6-7-21-8-9-22-10-11-23-12-13(17)18/h4-12H2,1-3H3,(H,16,19)(H,17,18)
InChIKey
SHMYENBXRNPSOG-UHFFFAOYSA-N
Biological Activity
Boc-NH-PEG4-CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[1]
Shipping
Room temperature
Boiling Point
493.6±40.0 °C at 760 mmHg