Description
Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid; HOOCCH2CH2O-PEG6-CH2CH2COOH; α,ω-Dipropionic acid hexaethylene glycol; 4,7,10,13,16,19,22-Heptaoxapentacosane-1,25-dioic acid
IUPAC Name
3-[2-[2-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES
C(COCCOCCOCCOCCOCCOCCOCCC(=O)O)C(=O)O
InChI
InChI=1S/C18H34O11/c19-17(20)1-3-23-5-7-25-9-11-27-13-15-29-16-14-28-12-10-26-8-6-24-4-2-18(21)22/h1-16H2,(H,19,20)(H,21,22)
InChIKey
AYUREXAVZVVOJM-UHFFFAOYSA-N
Solubility
Soluble in DMSO
Appearance
Pale Yellow or Colorless Oily Matter
Shipping
Room temperature, or blue ice upon request.
Storage
Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Boiling Point
572.8±50.0 °C at 760 mmHg