Atropine sulfate hydrate (2:1:1) - CAS 5908-99-6

Atropine sulfate hydrate (2:1:1) - CAS 5908-99-6 Catalog number: BADC-00239

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Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings, some types of slow heart rate, and to decrease saliva production during surgery.

ADCs Cytotoxin
Product Name
Atropine sulfate hydrate (2:1:1)
Catalog Number
Molecular Formula
Molecular Weight
Atropine sulfate hydrate (2:1:1)

Ordering Information

Catalog Number Size Price Quantity
BADC-00239 -- $--
Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings, some types of slow heart rate, and to decrease saliva production during surgery.
Atropine sulfate monohydrate; Atropini sulfas; Isopto Atropine; Atropinum sulphuricum; Atropine sulfate
[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate; sulfuric acid; hydrate
Canonical SMILES
Melting Point
Clinical Trial Information
NCT NumberTitleCondition Or DiseasePhaseStart DateSponsorStatus
NCT00947596A Study of Inhaled Atropine Sulfate in Healthy AdultsOrganophosphorus PoisoningPhase 1August 2009MicroDose Defense Products L.L.C.Completed
NCT01858090Intrathecal Levobupivacaine With Opioids for Caesarean SectionElective Caesarean Section SurgeriesPhase 3January 2009Baskent UniversityCompleted
NCT02078336Optimization of Procedural Sedation Protocol Used for Dental Care Delivery in People With Mental DisabilityDental Care for DisabledPhase 4December 2013Universitaire Ziekenhuizen LeuvenUnknown status
NCT03508817Atropine 0.01% Eye Drops in Myopia StudyMyopia, ProgressivePhase 1October 1, 2018Sultan Qaboos UniversityRecruiting
White Solid
Room temperature
Acute Toxic
Signal Word
1.Determination of diphenoxylate hydrochloride and atropine sulfate in combination drug formulations by liquid chromatography.
Lehr GJ1. J AOAC Int. 1996 Nov-Dec;79(6):1288-93.
An isocratic, reversed-phase liquid chromatographic (LC) method was developed for simultaneous determination of diphenoxylate hydrochloride (I) and atropine sulfate (II) in pharmaceutical products. Analysis is conducted on a Spherisorb CN column (5 microns), with a mobile phase consisting of 47% 0.001M pentanesulfonic acid sodium salt monohydrate, 53% acetonitrile, and 0.1% phosphoric acid. The detection wavelength is 220 nm. Tablets are extracted with acetonitrile-water (50 + 50). Oral solutions are determined directly after dilution. The method is validated for linearity, precision, system reproducibility, and accuracy. Recoveries at 80-120% of label claim ranged from 98.7 to 101.0% and from 99.6 to 102.5% for I and II, respectively. Results were linear (r > 0.9999) in the ranges 125-375 micrograms/mL and 1.25-3.75 micrograms/mL for I and II, respectively. Assay and content uniformity results for each ingredient, in both innovator products and generic formulations, are reported.
2.Endothelium-dependent contraction induced by acetylcholine in isolated rat renal arteries.
Nishimura Y1, Usui H, Kurahashi K, Suzuki A. Eur J Pharmacol. 1995 Mar 6;275(2):217-21.
We investigated whether or not acetylcholine elicited an endothelium-dependent contraction and whether an arachidonic acid metabolite was involved in the acetylcholine-induced contraction in ring preparations of rat renal arteries. Acetylcholine (0.1-100 microM) caused a transient contraction in endothelium-intact arteries in a concentration-dependent manner. The contraction induced by acetylcholine (10 microM) was enhanced by pretreatment with NG-nitro-L-arginine (100 microM), a nitric oxide synthase inhibitor, and was abolished by mechanical removal of the endothelium. Atropine (0.1 microM), quinacrine (1 and 3 microM), manoalide (0.1 and 1 microM), aspirin (1 and 10 microM), indomethacin (30 and 300 nM), ONO-3708 (9,11-dimethyl-methane-11,12-methano-13,14-dihydro-13-aza-14- oxo-15(beta)-cyclophenyl-omega-pentenor-thromboxane A2 L-arginine salt) (10 nM), S-1452 (calcium (5Z)-1R,2S,3S,4S-7-[3-phenylsulphonyl-aminobicyclo[2.2.1]hep t-2yl]-5- heptenoate hydrate) (3 nM) and SQ29,548 ([1S- [1 alpha,2 beta(5Z),3 beta,4 alpha]]-7-[3-[[2-[(phenylamino) carbonyl]hydrazino]methyl]-7-oxabicyclo[2.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2




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